Why are my observeEvent() functions in R Shiny unresponsive when reactive expressions are included in them?

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There could be several reasons why your observeEvent() functions in R Shiny are unresponsive when reactive expressions are included in them:

1. Synchronous execution: If the reactive expression inside observeEvent() takes a long time to execute, it can block the event handler from responding to input events. To solve this, you can use the reactivePoll() function to execute the reactive expression asynchronously and avoid blocking the event handler.

2. Incorrect reactivity: If the dependencies of the reactive expression inside observeEvent() are not specified correctly, the reactive expression may not update when expected, leading to unresponsive event handling. Make sure to include all the reactive inputs in the reactive expression's dependencies.

3. Race conditions: If multiple reactive expressions or event handlers are modifying the same reactive values simultaneously, it can lead to race conditions and unresponsive behavior. To avoid this, you can use reactiveValues() to create a shared state object that can be safely modified by multiple handlers.

4. Debugging: It's possible that there is an error in your code that is causing the issue. Try adding print statements at critical points in your code to debug the issue and isolate the root cause.

Overall, it's important to ensure that your reactive expressions and event handlers are properly structured and optimized for performance to avoid unresponsive behavior.