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Unfortunately, it is not possible to personalize the header title of an iframe when serving a PDF encoded using base64. The title of an iframe is typically set by the server hosting the content being displayed, and cannot be altered by the client side.
If you have control over the server hosting the PDF, you may be able to modify the headers sent with the file to set a custom title. However, this will not be possible if the PDF is being served from a third-party website or service.
One alternative solution could be to use JavaScript to dynamically set the title of the parent window based on the PDF content being displayed in the iframe. This would require you to parse the contents of the PDF and extract a suitable title to display.