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Yes, it is possible to refactor multiple assignments after checking for None type. Here is an example:

if my_variable is not None:
    a = my_variable.a
    b = my_variable.b
    c = my_variable.c

This can be refactored using tuple unpacking like this:

if my_variable is not None:
    a, b, c = my_variable.a, my_variable.b, my_variable.c

This way, the code is more concise and readable.