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Special characters may appear when writing a dataframe from Rstudio to Excel using RDCOMCLIENT due to encoding issues. Excel may use a different encoding for text compared to R, causing certain characters (e.g. non-ASCII characters, quotation marks, etc.) to appear differently in Excel. To avoid this, it is recommended to use a consistent encoding when working with text data in R and Excel or to specifically set the encoding when exporting the dataframe to Excel.