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Yes, the Microsoft Graph API provides a way to revoke the permissions granted by a personal user to your application. You can achieve this by calling the revokeOAuth2PermissionGrants API endpoint. The endpoint takes a user ID parameter, which identifies the user whose permissions you want to revoke, and an optional client ID parameter, which identifies the application for which you want to revoke the permissions. Once the permissions are revoked, the user will need to re-consent to grant them again.