Is it impossible to locate any element using Selenium?

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No, it is not impossible to locate any element using Selenium. However, there may be certain elements that cannot be located with standard locators and require alternative methods such as using JavaScript or image recognition. Additionally, elements may be located but may have dynamic IDs or location on the page which can make it more difficult to locate using Selenium. Overall, it is generally possible to locate most elements using Selenium with some creativity and knowledge of different locator strategies.