Is it not possible to generate a resource pool through the vSphere REST API?

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Yes, it is possible to generate a resource pool through the vSphere REST API. The vSphere REST API provides a set of endpoints that allow users to create, list and manage resource pools. To create a resource pool, you can use the POST /rest/vcenter/resource-pool endpoint and provide the required parameters such as the name, parent resource pool, and CPU/Memory allocation settings. You can also update and delete resource pools using the REST API.