Is it impossible to reach host ports using an IP address on a virtual NIC that was set up by Hyper-V?

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No, it is not impossible to reach host ports using an IP address on a virtual NIC set up by Hyper-V. However, it is important to ensure that the appropriate network settings are configured properly, such as enabling virtual network adapter sharing and allowing traffic through the firewall. Additionally, some network configurations may require additional setup or configuration to allow communication between the virtual machine and the host ports.